News
PhD Award

Doctoral degree awarded

Dr. Adriana Buskin was awarded her doctoral degree following the successful submission of her thesis and viva voce.

Latest funding

A new source of funding has been awarded from BBSRC UK

A new source of funding has been awarded from BBSRC UK to the group to assess SARS-CoV-2 entry, replication and prevention in a primary human conjunctival cell model and organ cultured cornea/conjunctiva.

Three new sources of funding have been awarded to the RSCR team

New funding from Medical Research Council UK, BBSRC UK and, the Childhood Eye Cancer Trust

“Elucidating splicing factor function and retinal splicing programmes: developing new therapeutic strategies for splicing factor retinitis pigmentosa”; funded by Medical Research Council UK to Lako, Johnson, Mozaffari-Jovin, Luehrmann, Urlaub, Nagaraja-Grellscheid and Ali groups.

“A single cell sequencing approach to determine the heterogeneity, dynamics and cell fate decisions of retinal progenitor cells in vivo and in vitro”; funded by BBSRC UK to Lako’s group.

“Assessing the feasibility of pluripotent stem cell derived retinal organoids as a model system to test the safety and efficacy of chemotherapeutic agents in Retinoblastoma”; funded by the Childhood Eye Cancer Trust to Lako and Parulekar groups.

Madeleine peddles coast-to-coast for charity

Coast-to-coast cycle event raises more than 21,000 for Retina UK.

Madeleine Carter from our group completed the coast-to-coast Hadrian’s wall tandem cycle event organised by www.RetinaUK.org.uk/tandemcycle and helped raise more than 21k pounds for the charity.

Latest funding awards

Two new sources of funding have been awarded to the RSCR team

Studying Ciliary Signaling in Development and Disease: Lako's group in collaboration with Newcells Biotech are part of a successful funding bid to H2020-MSCA-ITN-2019 SCilS: Studying Ciliary Signaling in Development and Disease.

Investigating the Development trajectories of progenitor cell populations in the human eye: Lako's group in collaboration with Prof. David Fitzpatrick's and Prof. Jane Sowden's is investigating the Development trajectories of progenitor cell populations in the human eye at single cell resolution through a successful funding award from MRC "scEye-Map".

ERC Project: Can we grow an artificial retina?

Majlinda Lako's research group has used human pluripotent stem cells for exactly this purpose.

Read more more on the European Reaseach Council website at https://erc.europa.eu/projects-figures/stories/can-we-grow-artificial-retina

Fight for Sight’s Christmas Appeal

New campaign focuses on treatments for children with eye cancer

Fight for Sight has launched a new campaign to raise awareness of the symptoms of retinoblastoma, and to raise funds for more research into eye conditions.

The campaign focuses on Kalli, a mum from Brecon in Wales who had the condition as a baby and lost an eye. Her eleven month-old daughter, Autumn, now has the condition too and they're taking part in research at Newcastle University funded by Fight for Sight.

Information about the campaign can be found on the Fight for Sight website. Please share this with your colleagues and help to raise funds for research into improved treatments for childhood eye cancer retinoblastoma.

Widespread errors in “proofreading” cause inherited blindness

A new paper from our group on Retinitis Pigmentosa appears in Nature Communication

Mistakes in “proofreading” the genetic code of retinal cells is the origin of a form of inherited blindness, retinitis pigmentosa (RP) caused by mutations in splicing factors, research has revealed.

This new understanding of the disease process, published in Nature Communications, is leading to the development of a gene therapy for RP caused by splicing factor defects.

Congratulations from our lab to to Adriana, Lili, Valeria and Joe for their hard work on this collaborative project with the University of Leeds, Durham and Max Planck Institute in Gottingen!

Read the full story from the Newcastle University press office:.

The published paper can be viewed here and downloaded as a pdf file.

New funding awards

Three new sources of funding have been awarded to the RSCR team

Fight for Sight funding: Assessing the feasibility of induced pluripotent stem cells to provide a disease model for Retinoblastoma.

RP Fighting Blindness funding: Investigating the role of alternative splicing in autosomal dominant retinitis pigmentosa using a PRPF31 patient specific induced pluripotent stem cell disease model.

Macular Society Funding: Exploiting the role of exosomes to treat age related macular degeneration and provide biomarkers for early diagnosis of the disease.

Light-responsive human retinal organoid model

The RSCR group has generated light responsive retinal organoids from human pluripotent stem cells.

Read more at PRWeb.

Biosciences Institute

Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3 BZ. United Kingdom

Tel: +44 (0)191 241 8688
Email: majlinda.lako@ncl.ac.uk

 

Newcastle University