Megaw E, Abu-Arafeh H, Mellough C, Gurniak-Witke C, Witke W, Dhillon B, Wright AF, Lako M and Ffrench-Constant C. (2017) Human induced pluripotent stem cell and animal models of X-linked retinitis pigmentosa identify impaired gelsolin activation as a cause of photoreceptor loss. Nature Communications: 8:271.

Chichagova V, Hallam D, Collin J, Buskin A, Saretzki G, Armstrong L, Yu-Man P, Lako M and Steel D (2017) Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A>G mitochondrial DNA mutation. Scientific Reports 26: 12320.

Kamarudin TA, Bojic S, Collin J, Yu M, Alharthi S, Buck H, Shortt A, Armstrong L, Figueiredo FC and Lako M. (2017) Differences in the activity of endogenous BMP signalling impact on the ability of induced pluripotent stem cells to differentiate to corneal epithelial like cells. Stem Cells (in press).

Hallam D, Collin J, Bojic S, Chichagova V, Buskin A, Yu X, Lafage L, Otten EG, Anyfantis G, Mellough C, Przyborski S, Alharthi S, Korolchuk V, Lotery A, Saretzki G, McKibbin M, Armstrong L, Steel D, Lako M. (2017) An iPSC patient specific model of CFH (Y402H) polymorphism displays characteristic features of AMD and indicates a beneficial role for UV light exposure. Stem Cells 35: 2305-2320.

Figueiredo GS, Bojic S, Rooney P, Wilshaw SP, Connon CJ, Gouveia RM, Paterson C, Lepert G, Mudhar HS, Figueiredo FC, Lako M. Gamma-irradiated human amniotic membrane decellularised with sodium dodecyl sulfate is a more efficient substrate for the ex vivo expansion of limbal stem cells. Acta Biomaterilia 2017; 61:124-133.

Hunt NC, Hallam D, Karimi A, Mellough CB, Steel DHW and Lako M. (2017) 3D culture of human pluripotent stem cells in RGD - alginate hydrogel improves retinal tissue development. Acta Biomaterilia 49: 329-343..

Zhu L, Gomez A, Saretzki G, Jin S, Tilgner K, Melguzo-Sanchiz D, Anyfantis G, Al-Aama J, Vallier L, Chinnery P, Lako M and Armstrong L (2016) CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages. J. Cell Biology 215(2):187-202.

Collin J, Mellough CB, Do rgau B, Pryzborki S, Moreno-Gimeno I and Lako M (2016) Using zinc finger nuclease technology to generate CRX-GFP reporter human embryonic stem cells as a tool to identify and study the emergence of photoreceptor precursors during pluripotent stem cell differentiation. Stem Cells 34: 311-21 (Cover page image)

Mellough CB and Lako M (2016) How to build a human. Elife. 24;5. pii: e19826.

Hunt NC and Lako M (2016) Tissue engineering using pluripotent stem cells: multidisciplinary approaches to accelerate bench-to-bedside transition. Regen Med. 6:495-8.

Chichagova V, Sanchez-Vera I, Armstrong L, Steel D, Lako M. (2016) Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population. Methods Mol Biol. 1353:285-307.

Mellough CB, Collin J, Khazim M, White K, Sernagor E, Steel D and Lako M (2015) IGF-1 signalling plays an important role in the formation of three dimensional laminated neural retina and other ocular structures from human embryonic stem cells. Stem Cells 33:2416-30 (Cover page image)

Megaw R, Mellough C, WRIGHT A, Lako M and Ffrench-Constant C (2015) Use of induced pluripotent stem cells technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa. Lancet Suppl 1:S69. doi: 10.1016/S0140-6736(15)60384-1.

Mellough CB, Collin J, Sernagor E, Wride NK, Steel DH and Lako M (2014) Lab generated retina: Realising the dream. Vision Neuroscience 22:1-16 (cover page image selected from our work described in this review).

Mellough CB, Sernagor E, Moreno-Gimeno, I, Steel DHW and Lako M (2012) Efficient stage-specific differentiation of human pluripotent stem cells towards retinal photoreceptor cells. Stem Cells 30:673-86 9 (front cover).

Armstrong L, Lako M, Buckley N, Lappin TR, Murphy MJ, Nolta JA, Pittenger M, Stojkovic M (2012). Editorial: Our top 10 developments in stem cell biology over the last 30 years. Stem Cells. 30:2-9.

Collin J, Lako M. (2011) Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells. Stem Cells. 29:1021-33.

Armstrong L, Tilgner K, Saretzki G, Atkinson SP, Stojkovic M, Moreno R, Przyborski S, Lako M.(2010) Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells. Stem Cells. 28:661-73.

Lako M, Armstrong L, Stojkovic M (2010). Induced pluripotent stem cells : it looks simple but can looks deceive? Stem Cells.28:845-50.

Mellough CB, Steel DH, Lako M. (2009) Genetic basis of inherited macular dystrophies and implications for stem cell therapy. Stem Cells. 27(11):2833-45.

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