Publications

Hunt NC, Hallam D, Karimi A, Mellough CB, Steel DHW and Lako M. (2016) 3D culture of human pluripotent stem cells in RGD - alginate hydrogel improves retinal tissue development. Acta Biomaterilia (in press).


Zhu L, Gomez A, Saretzki G, Jin S, Tilgner K, Melguzo-Sanchiz D, Anyfantis G, Al-Aama J, Vallier L, Chinnery P, Lako M and Armstrong L (2016) CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages. J. Cell Biology 215(2):187-202.


Collin J, Mellough CB, Do rgau B, Pryzborki S, Moreno-Gimeno I and Lako M (2016) Using zinc finger nuclease technology to generate CRX-GFP reporter human embryonic stem cells as a tool to identify and study the emergence of photoreceptor precursors during pluripotent stem cell differentiation. Stem Cells 34: 311-21 (Cover page image)


Mellough CB and Lako M (2016) How to build a human. Elife. 24;5. pii: e19826.


Hunt NC and Lako M (2016) Tissue engineering using pluripotent stem cells: multidisciplinary approaches to accelerate bench-to-bedside transition. Regen Med. 6:495-8.


Chichagova V, Sanchez-Vera I, Armstrong L, Steel D, Lako M. (2016) Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population. Methods Mol Biol. 1353:285-307.

Mellough CB, Collin J, Khazim M, White K, Sernagor E, Steel D and Lako M (2015) IGF-1 signalling plays an important role in the formation of three dimensional laminated neural retina and other ocular structures from human embryonic stem cells. Stem Cells 33:2416-30 (Cover page image)


Megaw R, Mellough C, WRIGHT A, Lako M and Ffrench-Constant C (2015) Use of induced pluripotent stem cells technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa. Lancet Suppl 1:S69. doi: 10.1016/S0140-6736(15)60384-1.


Mellough CB, Collin J, Sernagor E, Wride NK, Steel DH and Lako M (2014) Lab generated retina: Realising the dream. Vision Neuroscience 22:1-16 (cover page image selected from our work described in this review).


Mellough CB, Sernagor E, Moreno-Gimeno, I, Steel DHW and Lako M (2012) Efficient stage-specific differentiation of human pluripotent stem cells towards retinal photoreceptor cells. Stem Cells 30:673-86 9 (front cover).


Armstrong L, Lako M, Buckley N, Lappin TR, Murphy MJ, Nolta JA, Pittenger M, Stojkovic M (2012). Editorial: Our top 10 developments in stem cell biology over the last 30 years. Stem Cells. 30:2-9. https://www.ncbi.nlm.nih.gov/pubmed/22162299


Collin J, Lako M. (2011) Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells. Stem Cells. 29:1021-33.


Armstrong L, Tilgner K, Saretzki G, Atkinson SP, Stojkovic M, Moreno R, Przyborski S, Lako M.(2010) Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells. Stem Cells. 28:661-73.


Lako M, Armstrong L, Stojkovic M (2010). Induced pluripotent stem cells : it looks simple but can looks deceive? Stem Cells.28:845-50.


Mellough CB, Steel DH, Lako M. (2009) Genetic basis of inherited macular dystrophies and implications for stem cell therapy. Stem Cells. 27(11):2833-45.


Institute of Genetic Medicine and Institute for Ageing

Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3 BZ. United Kingdom

Tel: +44 (0)191 241 8688
Email: majlinda.lako@ncl.ac.uk

 

Newcastle University